Macro- and micro-environmental regulation of ectodermal organ stem cells
نویسندگان
چکیده
منابع مشابه
Ectodermal Organ Stem Cells: Morphogenesis, Population
Regenerative biology and medicine is emerging as one of the most fascinating fields with potentially high clinical applications. Nature is a rich resource from which to learn how to engineer stem cells for the application of regenerative medicine, particularly for integumentary ectodermal organs. Integumentary ectodermal organs include hairs, feathers, scales, horns, nails, claws, teeth, and gl...
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9 1. REVIEW OF THE LITERATURE 9 1.1. Ectodermal Organ Development 9 1.1.1. Origin of ectoderm 9 1.1.2. Common mechanisms in ectoderm 10 al organ development 1.1.3. Introduction to selected molecules with a central role in ectodermal organ development 10 1.1.3.1. Fgf, Bmp, Wnt, Shh pathways 10 1.1.3.2. Notch Pathway 13 1.1.3.3. Tnfs 16 1.1.3.3.1.Ectodysplasin pathway 18 1.1.4. Tooth development ...
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To accomplish regenerative medicine, several critical issues in stem cell biology have to be solved, including the identification of sources, the expanding population, building them into organs, and assimilating them to the host. Although many stem cells can now differentiate along certain lineages, knowledge on how to use them to build organs lags behind. Here we focus on topobiological events...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2009
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2009.05.089